Incucyte® Live-Cell Analysis Devices

To ensure accurate representation of cellular dynamics, it's important to optimize acquisition speed, resolution, and time intervals based on the specific biological phenomena being studied. However, over-collection of images can lead to excess data, increasing processing time and storage demands without necessarily enhancing biological insight. The ability to quickly capture images is crucial for studying fast kinetics in cellular activities.

Compare Incucyte® Live-Cell Analysis Systems

Make informed decisions about your cultures, rapidly optimize and improve your workflows, plus study complex live-cell assays to fast track your next discovery! Many technologies such as multi-mode readers and high-content imagers do not have the ability to maintain environmental control, meaning cells are not kept at physiologically relevant conditions. With advancements in modern high-resolution imaging techniques and the synthesis of fluorescent probes, it is now possible to view labeled sub-cellular structures at the nm scale. The Incucyte® Live-Cell Analysis System automatically monitors cells for days, weeks or even months as they sit stationary in the stable tissue culture incubator environment. Get answers to the most common questions about about Sartorius image and analysis solutions including critical information regarding instruments, applications, software, service, and more. Making advanced live-cell imaging technology accessible to all researchers is of critical importance.
If imaged over time, real-time dynamic data can be collected and events that could be missed with endpoint, fixed cell assays are captured. However, fixed (dead) cells cannot provide dynamic insights into biological function and do not represent living systems. Efforts to reduce the cost and complexity of live-cell imaging systems, along with the development of user-friendly software, will help to make these technologies more widely available. This will provide more comprehensive insights into cellular behavior and interactions within complex tissue structures. High-resolution images provide more detail but may require longer exposure times, which can be harmful to cells. These systems use high-definition microscopy to capture detailed, time-lapse images of cellular processes while incorporating features like noise reduction and artifact correction to improve image quality.

Request a Sample: Transfection Reagents for Life Science Research

The integrated software simplifies data analysis to accelerate response time, including the creation of publication-quality graphs and charts. Capture high-resolution fluorescence and brightfield images, recording data in real-time over hours, days, or weeks. Cells are dynamic in nature, so it is important to have the ability to image in real time to gain access to deeper biological insights. Traditional end-point assays only provide single measurement of cellular events. Live-cell imaging and analysis should be used when studying any area of cell therapeutics.

Fluorescence Microscopy in Live-Cell Imaging

Automated systems in live-cell analysis streamline image acquisition and processing, enabling efficient, accurate, and reproducible results. Fluorescence microscopy systems are designed to acquire images at high speeds, enabling researchers to observe rapid changes and dynamic processes in real-time. By tagging specific molecules with fluorescent markers, researchers can track their movement, concentration, and interactions within the cell, providing valuable data for understanding cellular mechanisms. The ability to selectively label and visualize specific molecules provides valuable insights into cellular processes that would otherwise be invisible. Efficient data management systems and advanced analytical tools are essential to handle this influx of information, enabling researchers to extract meaningful insights without being overwhelmed by the data.

• From 6-well to 384-well microtiter plates to standard tissue culture flasks, the Incucyte® can support your live-cell imaging and analysis needs.
• Reduce photobleaching and phototoxicity with patent-pending compact spinning disk technology all while operating within the controlled environment of an incubator
• Understanding these tradeoffs is essential for designing experiments that yield high-quality data without compromising cell health.
• Advanced imaging systems used in live-cell imaging are designed to minimize common issues such as focusing errors and image artifacts.
• Request a complimentary sample of our ready-to-use transfection reagents for life science research involving most mammalian cell lines.

When is live-cell imaging and analysis used?

This capability is essential for capturing transient events and understanding the temporal dynamics of cellular functions. Fluorescence microscopy allows for precise quantitative measurements of various cellular processes. This results in high-contrast images that clearly delineate different structures within the cell, making it easier to study their interactions and functions. Fluorescence microscopy enhances the visibility of cellular components by using fluorescent dyes or proteins that emit light when excited by specific wavelengths. Long-term live-cell imaging often involves repetitive tasks that can be efficiently managed through automation. Advanced environmental chambers and incubators are essential for creating stable and consistent conditions that support long-term cell culture.

Incucyte® devices for Cell Health and Proliferation

The content of our website is always available in English and partly in other languages. See how the Incucyte® can support your research needs, from setting up an assay to analyzing and exporting your data. Incucyte® S3 shares the same highest maximum throughput as the Incucyte® SX5 but supports only the phase channel as well as green and red fluorescence. For the Incucyte® S3, an incubator larger than 200L is recommended.

See What Your Cells Are Doing and When They Do It with the Incucyte® S3

• Live-cell imaging has become essential for studying the dynamic biology of living cells.
• Make the complex simple with powerful and integrated live-cell imaging and analysis tools that support your entire research team.
• This results in high-contrast images that clearly delineate different structures within the cell, making it easier to study their interactions and functions.
• Live-Cell Imaging and Analysis – Real-time, Quantitative and Inside your Incubator
• Live-cell imaging and analysis should be used when studying any area of cell therapeutics.
• Proper image optimization reduces noise and enhances the signal, making it easier to extract quantitative information from the images.

Quantitative fluorescence imaging enables the measurement of dynamic changes in real-time, offering a deeper understanding of cellular behavior. Derive meaningful data goatz casino no deposit bonus with sensitive, real-time live cell measurements made inside the stable condition of the incubator. Perform real-time, live-cell imaging and analysis of cell health, movement, morphology and function directly f… Make the complex simple with powerful and integrated live-cell imaging and analysis tools that support your entire research team. Easy-to-use software to support all scientists across variety of cell models – turn complex assays into reliable and objective publication-ready data
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The integration of 3D cell culture further enhances this approach by mimicking the structural complexity of living tissues, offering deeper insights into development, disease, and therapeutic response. Live-cell imaging has become essential for studying the dynamic biology of living cells. Make new discoveries with a wide range of applications  — from complex immune-tumor cell interactions, synaptic activity in neuronal co-cultures, metabolism in cancer cells, and much more.
The integration of AI and machine learning in live-cell imaging will enable quicker and deeper data mining. By enabling the study of living cells in their natural environment, live-cell imaging offers a more accurate and comprehensive view of biological processes. To ensure the best possible image quality, researchers must optimize various settings such as exposure time, focus, and illumination intensity. Optimizing assays for extended kinetic experiments is key to maintaining cell health and ensuring high-quality, reproducible imaging.